Synthroid is a synthetic medical analogue of hormone of the thyroid gland. It contains the active ingredient levothyroxine sodium which influences on the development and growth of tissues after partial metabolism in liver and kidneys and also improves metabolism.
The pharmacological characteristics of Synthroid are used in the medical practice to lower tumor of the thyroid gland and prevention of diseases caused by the hormone deficit of the thyroid gland.
In therapeutic doses, Synthroid regulates metabolism of protein, fats and carbohydrates, changes oxidation process in mitochondria, so that the body begins to better digest the fatty tissue. The use of Synthroid improves resistance of the central nervous system and stimulates the work of the cardiovascular system.

Indications for the use

Synthroid is used during pathological processes in the body which are caused by the hormone deficit in the thyroid gland.

  • Prevention and treatment of euthyroid diffuse goiter
  • Congenital dysfunction of the thyroid gland
  • Low mental and physical activity in the setting of hypothyroidism
  • Hypothyroidism
  • Prevention of relapses of nodular malignant tumors of thyroid gland after surgery

In what dose is Synthroid taken?

The dosage of Synthroid depends on the intensity of a disease and age of a patient. The treatment should be started from low doses and the dosage of Synthroid is gradually increased in order to achieve the optimal therapeutic effect. The dose is increased every 2-3 weeks during which changes of the thyroid gland and metabolic processes are controlled.

  • If hypothyroidism, the initial dose of Synthroid is 25-100 mcg per day
  • The maximal dose is 250 mcg per day for the treatment of hypothyroidism
  • The maintaining dose in the medical therapy of bronchocele is 100-200 mcg of Synthroid per day
  • After oncotomy of the malignant tumor of the thyroid gland, Synthroid is prescribed in the dose of 150-300 mcg per day
  • The daily dose of Synthroid is taken once, in the morning, before, or after eating.

Synthroid dosage for children:

  • Children under 1 year are recommended to use 6-10 mcg of Synthroid per 1 kg of the body weight
  • Children at the age of 1-5 are recommended to take 5-6 mcg per 1 kg of the body weight
  • Children at the age of 6-12 are prescribed Synthroid in the dose of 4-5 mcg per 1 kg of the body weight

Recommendations for the use

  • Do not use Synthroid during hyperfunction of the thyroid gland
  • In case of the acute myocardial infarction and also people with failure of the adrenal cortex Synthroid is contraindicated
  • Synthroid can be used during pregnancy, however, a woman should be examined by doctor regularly and control a development of fetus. In case of the potential danger of the pathology development, the treatment is ceased.
  • Patients with diabetes should take Synthroid with high caution because its action lowers therapeutic activity of insulin and hypoglycemic medicines


In case of overdose, a patient experiences increased level of the thyroid gland hormones and there is a chance of thyroid crisis. This is the most dangerous condition for human which can cause an acute heart failure and affection of the central nervous system.
The appearance of the overdose symptoms with Synthroid (tremor, tachycardia, pain in the chest, nervous agitation, fever, vomiting, and psychosis), it is necessary to stop the treatment and turn to a medical provider for the symptomatic treatment of the thyroid crisis.