Duloxetine – Active and Powerful Antidepressant

An effective selective serotonin and norepinephrine reuptake inhibitor Duloxetine serves an innovative antidepressant that manages the amounts of the brain chemicals that are unbalanced. Duloxetine is commonly prescribed as a treatment of major depressive disorders, anxiety, chronic joint or muscle pain, fibromyalgia and related disorders. Additionally, the medication can be taken in other cases not mentioned in the information leaflet. Consult your doctor before off-label Duloxetine use.

Essential Safety Concerns: Contraindications, Interactions and Precautions

Primarily to Duloxetine course, a patient should obligatorily talk to a healthcare provider and discuss all the possible issues and complications. Despite the treatment is considered to be safe, it can trigger undesirable reactions if misused or overused. Do not start the medication use if you are sensitive to the active ingredients of Duloxetine. In addition, pregnant and breastfeeding patients as well as the ones diagnosed with glaucoma should not administer the antidepressant. Duloxetine may cause dangerous side effects if used within 14 days after MAO inhibitor intake. Certain other health conditions may decrease or eliminate Duloxetine effect, especially:

  • Uncontrolled blood pressure;
  • Epilepsy, seizures, convulsions;
  • Kidney or liver dysfunctions;
  • Blood clots;
  • Manic depression;
  • Alcohol or drug addiction;
  • Narrow-angle glaucoma and others.

The treatment should not be used by patients under 18 years old. Otherwise, they risk experiencing severe health aggravations and other disorders.

Moreover, it is important to warn the doctor about other prescription and over-the-counter treatments you are using to avoid unnecessary interactions. Duloxetine should not be combined with:

  • Muscle relaxers;
  • Depression, anxiety, panic attack treatments;
  • Sleeping drugs;
  • Mood disorders medications;
  • Narcotic pain relievers;
  • Heart rhythm drugs;
  • Migraine headache remedies;
  • Blood thinners;
  • Antibiotics;
  • Cimetidine and others.

Proper Dosage and Intake – Key to Successful Treatment Course

Follow safety recommendations to make Duloxetine use beneficial and completely safe. The medication can be administered in various doses, depending on the condition. Nevertheless, averagely it is taken approximately at the same time daily. Keep using the drug for the full length of the prescribed course, since the first improvements may appear after 4-6 weeks of the treatment course. Sudden stopping of Duloxetine intake can trigger undesirable withdrawal effects. Once you have missed a pill, skip it if the following dose should be administered soon.

The common Duloxetine dose will differ greatly, based on the overall health condition of the patient, severity of his/her disorder and other factors. Thus, the initial Duloxetine dose usually reaches 30 mg, while the maximal one is 120 mg a day.

Duloxetine Side Effects and Undesirable Reactions

Call your doctor in case you have noticed any abnormalities after Duloxetine intake. Seek emergency medical assistance if the complications are severe, especially:

  • Allergic reactions;
  • Aggravated symptoms;
  • Lightheadedness, confusion, anxiety;
  • Urination disorders;
  • Vision impairments;
  • Increased serotonin levels in the organism;
  • Abnormal bleeding;
  • Liver of kidney problems;
  • Skin reactions;
  • Dangerous symptoms of the central nervous system disorders, etc.