A wide choice of antibiotics often confuses a regular consumer. Bear in mind that not all antibiotics are similarly effective and safe; and there is no need to buy a first available medicine. Before buying antibiotics, it is necessary to detect a site of the infection and have a laboratory blood test, if possible. If you do not know an originator of infection, the antibiotics of the broad spectrum action will work for you – Augmentin or Doxycycline.

According to the medical studies, the antibiotics from the group of penicillins and tetracycline are one of the most effective during the treatment of the infectious diseases. Augmentin and Doxycycline are not similar but they effectively cope with pathogenic microflora and can treat infection of any severity.

Before selecting an antibiotic, it is necessary to know how it works and whether it works in your case.


Augmentin is penicillin which contains clavulanic acid and amoxicillin. This acid enhances a resistance of amoxicillin and it is not destroyed under the action of microbial enzymes of beta-lactamase. Due to the two active ingredients in Augmentin, it acts more effectively than the common penicillin, and it can be used in the treatment of the different infectious processes. As to microorganisms, Augmentin provides a bactericidal action.

Doxycycline is an antibiotic from the group of tetracycline which acts bacteriostatically. It is effective as to some originators which have a resistance to the action of penicillin. For example, Doxycycline effectively blocks the activity of Treponema spp which is not sensitive to the action of Augmentin.

A drawback of penicillin is that many microorganisms quickly develop resistance. The tetracycline antibiotic Doxycycline has a completely different chemical structure and is synthesized from other types of fungi, and therefore it can effectively replace Augmentin.

However, if we compare Augmentin vs Doxycycline by their pharmacological characteristics, a penicillin antibiotic Augmentin more effectively neutralizes a pathogenic microflora. It happens by means of the bactericidal action of penicillin. Doxycycline only blocks a synthesis of new microorganisms and does not let them develop; and Augmentin completely destroys morbific cells with microflora, so that the risk of a relapse of infection is absent.

Another important aspect during selecting an antibiotic is its pharmacological safety. As Doxycycline acts in low doses (200-300 mg per day), a half-life is about 20 hours. Augmentin begins to work during the use of high doses (1-2 g per day) but the half-life of the active ingredients is by 2 times shorter than in Doxycycline. It means that a risk of the side effects is by 2 times lower in Augmentin.

Another important factor during the comparison of Augmentin vs Doxycycline is a safety of using in children. Augmentin can be used by children at any age. The peroral doses are prescribed 9 month-babies, and suspensions and suppositories are prescribed newborn babies at the age of 3 months. This is a completely safe medicine for children and will not cause side effects.


Doxycycline cannot be taken by children under 8 years. As many tetracyclines, this medicine can cause a formation of indissolvable complexes Ca2+ in the bone tissue of a child, so that there will be problems with enamel, bone tissue of skeletal system, and others. Therefore if you are selecting antibiotic for your child, you should select Augmentin.

Penicillin is working antibiotics which can be used as the first antibacterial aid. However, if you took Augmentin or other penicillin within the past 6 months, it is better to use Doxycycline. The risk of a resistance development will be low and the efficiency of the antibacterial therapy will be effective.